@article {7495,
	title = {Succeed Escape: Flow shear promotes tumbling of Escherichia colinear a solid surface},
	journal = { Scientific Reports},
	volume = {6},
	year = {2016},
	abstract = {Understanding how bacteria move close to a surface under various stimuli is crucial for a broad range of microbial processes including biofilm formation, bacterial transport and migration. While prior studies focus on interactions between single stimulus and bacterial suspension, we emphasize on compounding effects of flow shear and solid surfaces on bacterial motility, especially reorientation and tumble. We have applied microfluidics and digital holographic microscopy to capture a large number (\&gt;105) of 3D\&nbsp;Escherichia colitrajectories near a surface under various flow shear. We find that near-surface flow shear promotes cell reorientation and mitigates the tumble suppression and re-orientation confinement found in a quiescent flow, and consequently enhances surface normal bacterial dispersion. Conditional sampling suggests that two complimentary hydrodynamic mechanisms, Jeffrey Orbit and shear-induced flagella unbundling, are responsible for the enhancement in bacterial tumble motility. These findings imply that flow shear may mitigate cell trapping and prevent biofilm initiation.},
	url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082759/},
	author = {Molaei,Mehdi and Sheng, Jian}
}
